Epidural clonidine used as an adjunct to local anesthetics has a few distinct mechanisms of action. 1st, the stimulation of alpha-two-receptors while in the dorsal horn reduces agony transmission. Next, clonidine may cause area vasoconstriction that limits vascular removing of local epidural anesthetics. Jun 10, 2024 · If clonidine https://trevorgepok.develop-blog.com/42963085/onolidine-fundamentals-explained