Below, we clearly show that conolidine, a pure analgesic alkaloid used in traditional Chinese drugs, targets ACKR3, thus supplying added evidence of the correlation involving ACKR3 and agony modulation and opening alternate therapeutic avenues for that treatment of Long-term soreness. We shown that, in contrast to classical opioid receptors, https://conolidineahistoryofnatur99764.sharebyblog.com/30962688/not-known-details-about-what-is-conolidine