Pentobarbital will decrease the extent or influence of nitrendipine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Importance Unfamiliar. Barbiturates such as pentobarbital are addictive and have already been historically misused and abused illegally as Avenue drugs. Pentobarbital abuse can result in tolerance, dependence, and overdose, and induce withdrawal indicator... https://geralds009myk4.thelateblog.com/profile