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DNA ligases seal five′-PO4 and three′-OH polynucleotide finishes by using a few nucleotidyl transfer techniques involving ligase-adenylate and DNA-adenylate intermediates. DNA ligases are important guardians of genomic integrity, and ligase dysfunction underlies human genetic disorder syndromes. Crystal constructions of DNA ligases certain to nucleotide and nucleic acid substrates have https://www-ligaz-bet95825.bloggerchest.com/27938176/the-best-side-of-homepage-https-ligaz-bet

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